Description Food supplement containing carcinine, with anti-glycation, de-glycation and anti-ageing action.
Inhibition of the synergy between glycation and oxidation reactions.
Stopping of scavenging propagators (glucose, glyoxal, etc.).
Inhibition of lipid peroxidation.
Chelation of metal ions.
Anti-ageing skin treatment.
Properties Carcinine is more stable than carnosine, is not attacked by the enzyme carnosinase, nor converted into histidine. It is quickly assimilated and resistant to gastric pH and to skin, serum and tissue peptidases. It lasts longer in the body, which improves its effectiveness against glycation.
Ingredients Glycoless (carcinine dihydrochloride), Lithotame (Lithothamnion calcareum Areschoug) thallus powder, magnesium stearate, chromium picolinate, vegetable gelatin capsule (E171).
Nutritional information | Average values per 1 capsule |
|---|
| Glycoless | 200 mg |
| Lithotame | 200 mg |
| Magnesium stearate | 2 mg |
| Chromium picolinate | 1.66 mg |
How to use 1 capsule to be taken in the morning on an empty stomach.
Storage Store at a temperature not exceeding +25°C.
Shelf life in unopened pack: 36 months.
Size Pack of 15 capsules.
Code NOM
Bibliography 1. "The role of carcinine treatment on glycolipid imbalance of overweight and obese woman", Palmieri B., Pepe V., Simas L.a.w., Granzoti R., Novak B., Wolpe R.e., Zilbert B., Yamaguchi E.m., Vadalà M., Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic.
2. "A suplementação de carcinina e sua implicação na glicemia de jejum, hemoglobina glicada, insulina, frutosamina e perfil lipídico em mulheres com sobrepeso e obesidade: um ensaio clínico randomizado duplo-cego controlado por placebo". Simas, l.A.W.; Granzoti; r.; Novak, b; wolpe, r.E.; Zilbert, b.; Yamaguchi, e.M.
3. "L-Carnosine(-alanyl-L-histidine) and carcinine F-alanylhistamine) act as natural antioxidants with hydroxyl-radical-scavenging and lipid-peroxidase activities", Mark A. Babizhayev, Marie-Christine Seguin, Jean Gueynej, Rima P. Evstigneeva, Elena A. Ageyeva and Galina A. Zheltukhinai, Moscow Helmholtz Research Institute of Eye Diseases, Russia, and IM.V. Lomonosov Institute of Fine Chemical Technology, Russia, Exsymol S.A.M., Monaco, Principaute de Monaco.
4. "Carcinine Has 4-Hydroxynonenal Scavenging Property and Neuroprotective Effect in Mouse Retina", Lea D. Marchette, Huaiwen Wang, Feng Li, Mark A. Babizhayev, Anne Kasus-Jacobi, Departments of Ophthalmology, Molecular Biology Proteomics Facility, and Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
5. "Investigating Carcinine Transport and the Expression Profile of Transporter Genes in Human Corneal Epithelial Cells", Studies on the Cornea and Lens, pp 131-144, Anne Kasus-Jacobi (Department of Pharmaceutical Sciences and Oklahoma Center for Neuroscience), Vibudhuta Awasthi (Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences), Mark A. Babizhayev (Innovative Vision Products Inc., Moscow, Russia), H. Anne Pereira (Departments of Pharmaceutical Sciences, Pathology, and Cell Biology and Oklahoma Center for Neuroscience, University of Oklahoma Health Sciences Center, Oklahoma City, USA).
6. "Treatment of Skin Aging and Photoaging with Innovative Oral Dosage Forms of Non-Hydrolized Carnosine and Carcinine", Research Article ,International Journal of Clinical Dermatology & Research (IJCDR), Babizhayev Mark A. (Innovative Vision Products, Inc).
7. "Advanced Glycation End-Products and Their Receptor- Mediated Roles: Inflammation and Oxidative Stress", Parisa Younessi, Ali Yoonessi, Iran J Med Sci, September 2011; Vol 36 N. 3.
8. A. Pegova, "Comp. Biochem. Physiol.", vol. 127, (2000). pp. 443-446.
