Name
PANACUR TABLETS FOR DOGS AND CATS
Pharmacotherapeutic Group
Anthelmintics.
Active Ingredients
Each 250 mg and 500 mg tablet contains the active substance respectively: fenbendazole 250 mg; fenbendazole 500 mg.
Excipients
Lactose monohydrate, maize starch, colloidal anhydrous silica, hydroxyethylcellulose, sodium starch glycolate (type A), magnesium stearate.
Indications
Dogs. Treatment of the following gastrointestinal nematode and cestode infestations: roundworms (Toxocara canis, Toxascaris leonina), mature stages; hookworms (Ancylostoma caninum, Uncinaria stenocephala), mature stages; whipworms (Trichuris vulpis), mature stages; tapeworms (Taenia pisiformis), mature stages. Prevention and control of Giardia infestations. Cats. Treatment of gastrointestinal nematode and cestode infestations: roundworms (Toxocara cati), mature stages; hookworms (Ancylostoma tubaeforme), immature and mature stages; tapeworms (Taenia hydatigena), mature stages. It is advisable to repeat the treatment against roundworms and tapeworms, taking into account the development cycle of the parasite from larva to mature stage.
Contraindications/Side Effects
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Safety in Target Species
No data available.
Dosage
Oral use. The dosage for dogs and cats is 50 mg fenbendazole/kg body weight/day. Panacur 250 mg tablets: 1/2 tablet (= 125 mg fenbendazole) per 2.5 kg body weight; 1 tablet (= 250 mg fenbendazole) per 5 kg body weight. Panacur forte 500 mg tablets: 1/2 tablet (= 250 mg fenbendazole) per 5 kg body weight; 1 tablet (= 500 mg fenbendazole) per 10 kg body weight. The treatment must be repeated for 3 consecutive days. Dogs: crumble the tablets and mix them with food. The tablets can also be dissolved in a little water and the mixture added to the food. Cats: dissolve the tablets in a little water and mix with food. It is advisable to give the tablets mixed with a first portion of the daily food ration, to ensure they are completely consumed. Giving the tablets whole or dissolved in water to fasting animals is not recommended, to avoid a possible reduction in efficacy. Avoid giving milk at the same time. Underdosing could result in a lack of efficacy and may favour the development of resistance. To ensure correct dosing, determine body weight as accurately as possible.
Storage
Panacur 250 mg tablets: this veterinary medicinal product does not require any special storage conditions. Panacur forte 500 mg tablets: do not store above 25 °C. Shelf life of the veterinary medicinal product as packaged for sale: 3 years.
Warnings
The tablets have a neutral taste. For both animal species, to achieve effective control of gastrointestinal nematodes, cestodes and giardiasis in dogs, treatment should be based on the results of a faecal parasitological examination. Unnecessary use of antiparasitics or use deviating from the instructions given in this summary of product characteristics may increase the resistance selection pressure and reduce efficacy. The decision to use the veterinary medicinal product should be based on confirmation of the parasitic species and burden, or of the risk of infestation based on its epidemiological features, for each individual animal. Care should be taken to avoid the following practices, which increase the risk of development of resistance and could ultimately result in ineffective therapy: too frequent and repeated use of anthelmintics from the same class over an extended period of time; underdosing of the veterinary medicinal product, which may be due to underestimation of the animal's body weight, incorrect administration of the product or lack of calibration of the dosing device. It is also advisable to check the success of the treatment (for example by monitoring the clinical appearance and faecal egg counts). Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate methods (e.g. the faecal egg count reduction test (FECRT)). Where the results of diagnostic tests clearly indicate resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used. Special precautions for safe use in the target species: the possibility that other animals in the same household may be a source of reinfestation with gastrointestinal nematodes should be considered, and these should be treated as necessary with a suitable veterinary medicinal product. Special precautions to be taken by the person administering the veterinary medicinal product to animals: wash hands after use. Do not eat, drink or smoke during administration. This veterinary medicinal product may be toxic if swallowed by humans. This veterinary medicinal product may cause hypersensitivity reactions. Avoid contact with skin, eyes and mucous membranes. Always wear protective gloves when handling the veterinary medicinal product. In case of contact with skin and/or eyes, rinse immediately with plenty of water. Remove clothing contaminated with the product. Special precautions for the protection of the environment: not applicable. No data available. Incompatibilities: none known.
Withdrawal Period
Not applicable.
Target Species
Dog, cat (adults and puppies/kittens).
Interactions
None known.
Diagnosis and Prescription
Veterinary medicinal product not subject to prescription.
Side Effects
Dogs. Rare (1 to 10 animals / 10,000 animals treated): gastrointestinal disorders (e.g. vomiting and diarrhoea ^1); very rare (< 1 animal / 10,000 animals treated, including isolated reports): allergic reaction. ^1 Diarrhoea is usually mild. Cats. Very rare (< 1 animal / 10,000 animals treated, including isolated reports): gastrointestinal disorders (e.g. vomiting and diarrhoea ^1). ^1 Diarrhoea is usually mild. Reporting adverse events is important as it allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to the marketing authorisation holder or its local representative or to the national competent authority via the national reporting system. See also the package leaflet for the respective contact details.
Pregnancy and Lactation
Do not use in pregnant animals. In the absence of studies in the target species, during lactation use only according to the benefit-risk assessment by the responsible veterinarian.
